Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.72 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669093 | 0.85 | ITGB3 (0.73) | ITGB3ITGA2BITGAVABCG2ABCB1 | |
| SCHEMBL7669111 | 0.85 | ITGB3 (0.73) | ITGB3ITGA2BITGAVABCG2ABCB1 | |
| SCHEMBL7437403 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGAVABCG2ABCB1 | |
| SCHEMBL7437406 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGAVABCG2ABCB1 | |
| SCHEMBL7669121 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2BITGAVABCG2ABCB1 | |
| SCHEMBL7440009 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BDRD2 | |
| SCHEMBL7440013 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BDRD2 | |
| SCHEMBL7437422 | 0.81 | ITGB3 (0.77) | ITGB3ITGA2BITGAVABCG2ABCB1 | |
| SCHEMBL7450755 | 0.76 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7450753 | 0.76 | ITGB3 (0.69) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |