Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667833 | 0.88 | BRD4 (0.50) | BRD4ALDH1A1PKMSMN1; SMN2TMEM97 | |
| SCHEMBL14175058 | 0.77 | MAPT (0.47) | BRD4ALDH1A1PKMSMN1; SMN2GAA | |
| SCHEMBL8547801 | 0.77 | BRD4 (0.50) | BRD4ALDH1A1SMN1; SMN2TMEM97GAA | |
| SCHEMBL13947941 | 0.77 | BRD4 (0.48) | BRD4ALDH1A1PKMSMN1; SMN2TMEM97 | |
| SCHEMBL1060677 | 0.71 | PTPN1 (0.47) | ALDH1A1PKMSMN1; SMN2GAANPC1 | |
| SCHEMBL16313522 | 0.70 | CYP1A2 (0.56) | ALDH1A1PKMSMN1; SMN2GAANPC1 | |
| SCHEMBL31298081 | 0.70 | HDAC6 (0.50) | HDAC3 | |
| SCHEMBL743549 | 0.69 | CES2 (0.58) | ALDH1A1PKMSMN1; SMN2GAANPC1 | |
| SCHEMBL12926147 | 0.69 | ERCC5 (0.54) | ALDH1A1PKMSMN1; SMN2HDAC3NPC1 | |
| SCHEMBL8478724 | 0.69 | GAA (0.44) | ALDH1A1PKMSMN1; SMN2HDAC3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355641-B1 | HYPOTENSIVE AGENTS AND WOUND HEALING AGENTS | SYNTEX (U.S.A.) LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2000055143-A1 | OXAZOLONE DERIVATIVES AND THEIR USE AS ALPHA-1 ADRENORECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-09-21 | — | — | WO | disclosed |