Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175058 | 0.86 | MAPT (0.47) | BRD4CES2CES1GFERPOLB | |
| SCHEMBL362234 | 0.82 | ALDH1A1 (0.50) | CES2CES1GFERPOLBALDH1A1 | |
| SCHEMBL7667833 | 0.82 | BRD4 (0.50) | BRD4CES2CES1GFERTMEM97 | |
| SCHEMBL13947941 | 0.80 | BRD4 (0.48) | BRD4CES2CES1GFERTMEM97 | |
| SCHEMBL1060677 | 0.79 | PTPN1 (0.47) | CES2CES1GFERPOLBALDH1A1 | |
| SCHEMBL13381405 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL743549 | 0.77 | CES2 (0.58) | CES2CES1GFERPOLBALDH1A1 | |
| SCHEMBL7669137 | 0.77 | BRD4 (0.52) | BRD4GFERTMEM97ALDH1A1GAA | |
| SCHEMBL226605 | 0.76 | CES2 (0.56) | CES2CES1GFERPOLBALDH1A1 | |
| SCHEMBL13562671 | 0.76 | KMT2A (0.47) | CES2CES1TMEM97POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724503-B1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING & MFG (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5736747-A | SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5733648-A | FOR AMINOPLASTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5710281-A | Organic compounds suitable as reactive diluents and binder precursor compositions including same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5709935-A | ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5667842-A | Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5580647-A | OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0724503-A1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5523152-A | Organic compounds suitable as reactive diluents, and binder precursor compositions including same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995011774-A1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-04 | — | — | WO | disclosed |