SCHEMBL7669189

SCHEMBL7669189

CC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 13/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4503644 0.94 CACNA1B (0.65) CACNA1B
SCHEMBL7267420 0.85 CACNA1B (0.68) CACNA1B
SCHEMBL11867712 0.84 ALDH1A1 (0.57) CACNA1B
SCHEMBL7266484 0.83 CACNA1B (0.73) CACNA1B
SCHEMBL7275400 0.83 CACNA1B (0.67) CACNA1B
SCHEMBL7266091 0.83 CACNA1B (0.54) CACNA1B
SCHEMBL7272993 0.83 CACNA1B (0.54) CACNA1B
SCHEMBL7265857 0.82 CACNA1B (0.53) CACNA1B
SCHEMBL7266526 0.82 CACNA1B (0.53) CACNA1B
SCHEMBL7267485 0.81 CACNA1B (0.53) CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6350762-B1 SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; AJINOMOTO CO., INC. (JP) 2002-02-26 US disclosed
EP-1043314-A1 NOVEL DIHYDROPYRIDINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2000-10-11 EP disclosed
CN-1261348-A Dihydropyridine derivatives AJINOMTO CO INC (JP) 2000-07-26 CN disclosed