Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272104 | 0.88 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL7267442 | 0.87 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL4503644 | 0.86 | CACNA1B (0.65) | CACNA1B | |
| SCHEMBL7265406 | 0.82 | CACNA1F (0.48) | CACNA1BHTT | |
| SCHEMBL7265490 | 0.82 | CACNA1F (0.57) | CACNA1B | |
| SCHEMBL7275626 | 0.82 | CACNA1F (0.48) | CACNA1B | |
| SCHEMBL7669189 | 0.81 | CACNA1B (0.61) | CACNA1B | |
| SCHEMBL7267803 | 0.80 | CACNA1B (0.41) | CACNA1B | |
| SCHEMBL7275870 | 0.79 | CACNA1B (0.38) | CACNA1BHTT | |
| SCHEMBL7265623 | 0.78 | CYP2C9 (0.49) | CACNA1BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |