Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658100 | 0.91 | CMA1 (0.45) | CMA1 | |
| SCHEMBL7663175 | 0.86 | CYP3A4 (0.45) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL7668441 | 0.86 | CAPN1 (0.44) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL7665843 | 0.85 | CTSD (0.41) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL5711332 | 0.85 | CAPN1 (0.46) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL7668192 | 0.85 | CAPN1 (0.49) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL7664531 | 0.83 | CAPN1 (0.48) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL7662695 | 0.82 | CAPN1 (0.45) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL7662824 | 0.80 | CTSD (0.49) | CAPN1CYP3A4CTSBCTSKCTSL | |
| SCHEMBL5711319 | 0.79 | CAPN1 (0.50) | CAPN1CYP3A4CTSBCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |