Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662824 | 0.94 | CTSD (0.49) | CAPN1CTSLCTSBCTSKCCR1 | |
| SCHEMBL7658041 | 0.93 | CTSL (0.44) | CAPN1CTSLCTSBCTSKCCR1 | |
| SCHEMBL7668101 | 0.91 | PREP (0.48) | CAPN1PREPCYP3A4DPP4ELANE | |
| SCHEMBL7664531 | 0.90 | CAPN1 (0.48) | CAPN1CTSLCTSBCTSKCCR1 | |
| SCHEMBL7664392 | 0.90 | ELANE (0.47) | CCR1CMA1ELANE | |
| SCHEMBL7659218 | 0.89 | CMA1 (0.52) | CMA1 | |
| SCHEMBL7669769 | 0.89 | CASP1 (0.43) | CTSDPREPCYP3A4DPP4TRPM8 | |
| SCHEMBL7670975 | 0.89 | DPP4 (0.49) | CTSLCTSBCTSKPREPCYP3A4 | |
| SCHEMBL7655898 | 0.89 | ACE2 (0.46) | CTSDCMA1 | |
| SCHEMBL7670814 | 0.88 | REN (0.49) | CAPN1CTSLCTSBCTSKPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |