SCHEMBL766925

SCHEMBL766925

Cc1nc2cc3nsnc3cc2nc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.39
MAPT P10636 4/20 0.38
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
APAF1 O14727 1/20 0.38
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
NR4A1 P22736 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HSD17B10 Q99714 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13388977 0.83 TDP1 (0.46) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL19733725 0.76 PTPN11 (0.41) PTPN11MAPTALDH1A1KMT2AMEN1
SCHEMBL367773 0.75 PTPN11 (0.44) PTPN11MAPTALDH1A1KMT2AMEN1
SCHEMBL3258463 0.74 PTPN11 (0.48) PTPN11MAPTALDH1A1KMT2AMEN1
SCHEMBL31429032 0.71 TDP1 (0.43) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL2490986 0.71 NQO2 (0.57) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL19757341 0.70 SMN1; SMN2 (0.72) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL17652916 0.68 NQO2 (0.68) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL19364887 0.67 MAPT (0.38) PTPN11MAPTALDH1A1KMT2AMEN1
SCHEMBL1259520 0.67 HRH4 (0.52) MAPTALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108573995-B Light-emitting display device 三星显示有限公司 2023-07-14 CN disclosed
US-20210163677-A1 PHOTOACTIVE MATERIALS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2021-06-03 US disclosed
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 US disclosed
US-9412949-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2016-08-09 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed
US-7842758-B2 Conjugated materials featuring proquinoidal units THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-11-30 US disclosed
WO-2010075512-A1 POLYMERS WITH BODIPY-BASED BACKBONE FOR SOLAR CELLS MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2010-07-01 WO disclosed
WO-2010075514-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2010-07-01 WO disclosed
US-20090221762-A1 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS THE TRUSSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-09-03 US disclosed
WO-2007081991-A9 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS UNIV PENNSYLVANIA (US) 2007-09-07 WO disclosed
WO-2007081991-A2 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221762-A1 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS PML, ILK, PARG PTPN11 4686/4885MAPT 83/4885ALDH1A1 2833/4885
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 PTPN11 4268/4885MAPT 1232/4885ALDH1A1 2651/4885
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 PTPN11 4268/4885MAPT 1232/4885ALDH1A1 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.