Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333061 | 0.85 | TBXAS1 (0.78) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29403620 | 0.85 | TBXAS1 (0.78) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL305976 | 0.84 | TBXAS1 (0.79) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27446829 | 0.84 | TBXAS1 (0.76) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27939457 | 0.83 | TBXAS1 (0.64) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| Potassium Ion SCHEMBL27486991 | 0.82 | TBXAS1 (0.58) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| Lithium Ion SCHEMBL987070 | 0.82 | TBXAS1 (0.58) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5310336 | 0.81 | NAPRT (0.72) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL83186 | 0.80 | RECQL (0.62) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1283208 | 0.80 | TBXAS1 (0.60) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |
| WO-2023178378-A1 | MIP INHIBITORS | DMTC Limited (AU) | 2023-09-28 | — | — | WO | disclosed |