Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL27486991 | 0.96 | TBXAS1 (0.58) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| Lithium Ion SCHEMBL986768 | 0.83 | NAPRT (0.69) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27939457 | 0.83 | TBXAS1 (0.64) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7669273 | 0.82 | TBXAS1 (0.63) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29403620 | 0.81 | TBXAS1 (0.78) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL333061 | 0.81 | TBXAS1 (0.78) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4200852 | 0.81 | TBXAS1 (0.57) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL83186 | 0.80 | RECQL (0.62) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL305976 | 0.80 | TBXAS1 (0.79) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL868044 | 0.80 | TBXAS1 (0.60) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428660-B | Process for producing acetic acid | 国际人造丝公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-107207392-B | Process for producing acetic acid | 国际人造丝公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-108349865-B | Process for producing acetic acid | 国际人造丝公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-107207391-B | Process for producing acetic acid | 国际人造丝公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3277654-B1 | PROCESSES FOR PRODUCING ACETIC ACID | CELANESE INT CORP (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3374342-B1 | PROCESSES FOR PRODUCING ACETIC ACID | CELANESE INT CORP (US) | 2020-07-08 | — | — | EP | disclosed |
| EP-3250545-B1 | PROCESSES FOR PRODUCING ACETIC ACID | CELANESE INT CORP (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-3374342-A1 | PROCESSES FOR PRODUCING ACETIC ACID | Celanese International Corporation (US) | 2018-09-19 | — | — | EP | disclosed |
| US-9957216-B2 | Processes for producing acetic acid | CELANESE INTERNATIONAL CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| EP-3277654-A1 | PROCESSES FOR PRODUCING ACETIC ACID | Celanese International Corporation (US) | 2018-02-07 | — | — | EP | disclosed |
| US-8455685-B2 | Acetic anhydride production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-20130102809-A1 | Methanol Carbonylation Process with Rhodium Catalyst, an Iodide Salt and a Metallic Co-Catalyst Selected from Transition Metals, Indium, Strontium, Barium, Zinc, Tin and Heteropoly Acids | CELANESE INTERNATIONAL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102810-A1 | Methanol Carbonylation Process with Rhodium Catalyst and a Lanthanide Metal Co-Catalyst | CELANESE INTERNATIONAL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-20120183450-A1 | ACETIC ACID PRODUCTION BY WAY OF CARBONYLATION WITH ENHANCED REACTION AND FLASHING | SCATES MARK O (US) | 2012-07-19 | — | — | US | disclosed |
| EP-2451766-A2 | ACETIC ACID PRODUCTION BY WAY OF CARBONYLATION WITH ENHANCED REACTION AND FLASHING | Celanese International Corporation (US) | 2012-05-16 | — | — | EP | disclosed |
| US-8168822-B2 | Acetic acid production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION (US) | 2012-05-01 | — | — | US | disclosed |
| WO-2011159268-A1 | CARBONYLATION PROCESS | CELANESE INTERNALTIONAL CORPORATION (US) | 2011-12-22 | — | — | WO | disclosed |
| US-20110021816-A1 | Acetic anhydride production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION | 2011-01-27 | — | — | US | disclosed |
| US-20110009665-A1 | Acetic acid production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION | 2011-01-13 | — | — | US | disclosed |
| WO-2011005304-A2 | ACETIC ACID PRODUCTION BY WAY OF CARBONYLATION WITH ENHANCED REACTION AND FLASHING | CELANESE INTERNATIONAL CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009665-A1 | Acetic acid production by way of carbonylation with enhanced reaction and flashing | DNMT1, SP1, ME1 | TBXAS1 2880/4885NAPRT 4001/4885CYP1A2 381/4885 |
| US-20130102809-A1 | Methanol Carbonylation Process with Rhodium Catalyst, an Iodide Salt and a Metallic Co-Catalyst Selected from Transition Metals, Indium, Strontium, Barium, Zinc, Tin and Heteropoly Acids | CCNY, CA9, CA3 | TBXAS1 3836/4885NAPRT 3524/4885CYP1A2 637/4885 |
| US-20110021816-A1 | Acetic anhydride production by way of carbonylation with enhanced reaction and flashing | CA3, CA4, CA2 | TBXAS1 2523/4885NAPRT 4568/4885CYP1A2 559/4885 |
| US-20130102810-A1 | Methanol Carbonylation Process with Rhodium Catalyst and a Lanthanide Metal Co-Catalyst | ME1, MLYCD, SP1 | TBXAS1 4494/4885NAPRT 4336/4885CYP1A2 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.