Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.65 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 6/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665464 | 0.90 | MRGPRX4 (0.54) | MRGPRX4RXRARXRBF2F10 | |
| SCHEMBL7670816 | 0.88 | F10 (0.67) | MRGPRX4F2F10NR4A2NR1H4 | |
| SCHEMBL7454069 | 0.86 | F2 (0.70) | MRGPRX4F2F10NR4A2NR1H4 | |
| SCHEMBL8072969 | 0.82 | F2 (0.54) | MRGPRX4F2F10TP53PKM | |
| SCHEMBL7660470 | 0.81 | F2 (0.63) | MRGPRX4F2F10NR4A2NR1H4 | |
| SCHEMBL7664103 | 0.80 | F10 (0.62) | MRGPRX4F2F10NR4A2 | |
| SCHEMBL21234292 | 0.79 | MRGPRX4 (1.00) | MRGPRX4RXRARXRBTP53PKM | |
| SCHEMBL7662094 | 0.78 | F10 (0.46) | F2F10 | |
| SCHEMBL7658103 | 0.77 | F2 (0.53) | MRGPRX4F2F10SMN1; SMN2RAB9A | |
| SCHEMBL7449570 | 0.77 | F2 (0.68) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |