Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 10/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714662 | 0.83 | MAPK8 (0.80) | MAPK8MAPK9MAPK10HTT | |
| SCHEMBL7666534 | 0.81 | MAPK8 (0.63) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL7003196 | 0.77 | LY96 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7676325 | 0.77 | LY96 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6999443 | 0.75 | KMT2A (0.54) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL7674081 | 0.74 | KMT2A (0.55) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7674085 | 0.74 | KMT2A (0.55) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL19427487 | 0.73 | MEN1 (0.62) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL19427445 | 0.73 | ALDH1A1 (0.75) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6868625 | 0.73 | MEN1 (0.63) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |