SCHEMBL7669798

SCHEMBL7669798

CCN(Cc1cccnc1)C(=S)NC

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.55
CHRNA4 P43681 2/20 0.55
ALDH1A1 P00352 6/20 0.53
KDM4E B2RXH2 2/20 0.53
LMNA P02545 1/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.51
ATM Q13315 1/20 0.51
MAPK1 P28482 1/20 0.50
TRPM8 Q7Z2W7 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7669395 0.89 KMT2A (0.54) CHRNB2CHRNA4ALDH1A1KDM4ELMNA
SCHEMBL7671824 0.88 KMT2A (0.67) ALDH1A1LMNAKMT2AMEN1MAPK1
SCHEMBL7671855 0.86 KMT2A (0.53) CHRNB2CHRNA4ALDH1A1KDM4ELMNA
SCHEMBL7662014 0.82 KDM4E (0.55) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL7657551 0.82 SMN1; SMN2 (0.62) CHRNB2CHRNA4ALDH1A1LMNAKMT2A
SCHEMBL7665506 0.81 KDM4E (0.49) CHRNB2CHRNA4ALDH1A1KDM4EKMT2A
SCHEMBL10512292 0.81 CHRNB2 (0.51) CHRNB2CHRNA4ALDH1A1KMT2AMEN1
SCHEMBL10995847 0.80 ALDH1A1 (0.61) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL10993687 0.80 MAPK1 (0.58) ALDH1A1LMNAKMT2AMEN1MAPK1
SCHEMBL7667346 0.79 CHRNB2 (0.54) CHRNB2CHRNA4ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed