Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204588 | 0.78 | POLB (0.53) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL3867080 | 0.73 | TLR7 (0.42) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL7035381 | 0.72 | NPSR1 (0.46) | LMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL12413754 | 0.70 | TP53 (0.48) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL3350693 | 0.70 | TLR7 (0.47) | TLR7POLBPDE4DLMNAHRH2 | |
| Hydrochloric Acid SCHEMBL9602331 | 0.70 | TLR7 (0.56) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL1026002 | 0.69 | APAF1 (0.67) | POLBLMNASMN1; SMN2APAF1TDP1 | |
| SCHEMBL7025957 | 0.69 | TLR7 (0.46) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL564029 | 0.69 | TLR7 (0.59) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL29379266 | 0.69 | TLR7 (0.59) | TLR7POLBPDE4DLMNAHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495583-B1 | DRUG FOR TREATING AN ALPHA-2 ADRENERGIC RECEPTOR ASSOCIATED DISORDER, NASAL CONGENSTION AND ALLEVIATING PAIN | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-12-17 | — | — | US | disclosed |