Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870842 | 0.84 | CYP11B1 (0.41) | POLBLMNACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL13782270 | 0.81 | CYP11B1 (0.46) | POLBLMNAADORA2ACYP11B1CYP11B2 | |
| SCHEMBL7669922 | 0.78 | TLR7 (0.45) | POLBLMNATLR7PDE4DHRH2 | |
| SCHEMBL9883961 | 0.78 | CYP11B1 (0.44) | POLBLMNAPDE4DADORA2ACYP11B1 | |
| SCHEMBL9883726 | 0.77 | CYP11B1 (0.43) | POLBLMNATLR7CYP11B1CYP11B2 | |
| SCHEMBL3042764 | 0.74 | PTGS2 (0.48) | CYP11B1CYP11B2APAF1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9602331 | 0.74 | TLR7 (0.56) | POLBLMNATLR7PDE4DHRH2 | |
| SCHEMBL18762215 | 0.74 | MEN1 (0.41) | PDE4DADORA2ACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1026002 | 0.74 | APAF1 (0.67) | POLBLMNACYP11B1CYP11B2APAF1 | |
| SCHEMBL564029 | 0.73 | TLR7 (0.59) | POLBLMNATLR7PDE4DHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045688-A1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-17 | — | — | WO | disclosed |