Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6986088 | 0.99 | CAMK2D (0.37) | CAMK2DIDH1CCNT1CDK9ALDH1A1 | |
| SCHEMBL7678555 | 0.85 | CCNT1 (0.42) | CAMK2DCCNT1CDK9GSK3BPIM1 | |
| SCHEMBL6979590 | 0.85 | CCNT1 (0.42) | CAMK2DIDH1CCNT1CDK9GSK3B | |
| SCHEMBL7826749 | 0.85 | CAMK2D (0.40) | CAMK2DIDH1SHMT2GSK3BPIM1 | |
| Hydrochloric Acid SCHEMBL6984455 | 0.85 | CCNT1 (0.42) | CAMK2DCCNT1CDK9GSK3BPIM1 | |
| SCHEMBL7676681 | 0.84 | CAMK2D (0.47) | CAMK2DCCNT1CDK9GSK3BPIM1 | |
| SCHEMBL6980550 | 0.83 | PRKACA (0.46) | CAMK2DCCNT1CDK9GSK3BPIM1 | |
| SCHEMBL7672205 | 0.83 | CAMK2D (0.48) | CAMK2DCCNT1CDK9PIM1TSHR | |
| SCHEMBL7678323 | 0.82 | CCNT1 (0.40) | CAMK2DIDH1CCNT1CDK9GSK3B | |
| SCHEMBL7670227 | 0.82 | PIM1 (0.43) | CAMK2DIDH1CCNT1CDK9GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |