Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670231 | 0.85 | CAMK2D (0.38) | CAMK2DIDH1SHMT2GSK3BPIM1 | |
| Hydrochloric Acid SCHEMBL6986088 | 0.84 | CAMK2D (0.37) | CAMK2DIDH1SHMT2GSK3BPIM1 | |
| SCHEMBL7826748 | 0.81 | PRKCA (0.46) | CAMK2DIDH1CDK4PRKACAPRKACG | |
| SCHEMBL7007161 | 0.73 | CAMK2D (0.57) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL6977921 | 0.70 | PIM1 (0.42) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL7007072 | 0.69 | PRKCA (0.45) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL7678555 | 0.68 | CCNT1 (0.42) | CAMK2DPRKACAPRKACGPRKACBGSK3B | |
| SCHEMBL6979590 | 0.68 | CCNT1 (0.42) | CAMK2DIDH1CDK4PRKACAPRKACG | |
| Hydrochloric Acid SCHEMBL6984455 | 0.68 | CCNT1 (0.42) | CAMK2DPRKACAPRKACGPRKACBGSK3B | |
| SCHEMBL21591527 | 0.68 | MEN1 (0.46) | SHMT2KDM4ELMNAHTTCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | claimed |