Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661207 | 0.81 | RXFP1 (0.42) | RXFP1TP53THRBPOLBALDH1A1 | |
| SCHEMBL7671814 | 0.78 | RXFP1 (0.40) | RXFP1TP53THRBPOLBALDH1A1 | |
| SCHEMBL370336 | 0.73 | TDP1 (0.46) | RXFP1TP53THRBALDH1A1HTT | |
| SCHEMBL4422412 | 0.72 | ALDH1A1 (0.49) | RXFP1TP53THRBPOLBALDH1A1 | |
| SCHEMBL7665836 | 0.71 | RXFP1 (0.45) | RXFP1TP53THRBKDM4E | |
| SCHEMBL17372395 | 0.71 | RXFP1 (0.50) | RXFP1TP53THRBALDH1A1HTT | |
| SCHEMBL2468516 | 0.69 | RXFP1 (0.42) | RXFP1TP53THRBALDH1A1HTT | |
| SCHEMBL8283565 | 0.67 | RXFP1 (0.41) | RXFP1TP53THRBALDH1A1HTT | |
| SCHEMBL17371920 | 0.66 | BUB1 (0.43) | RXFP1POLBALDH1A1KDM4E | |
| SCHEMBL4325559 | 0.66 | CYP2C19 (0.45) | RXFP1TP53THRBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395766-B1 | COGNITION ACTIVATORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-05-28 | — | — | US | disclosed |