Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454181 | 0.91 | NPC1 (0.38) | GPR27RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2154184 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2HPGDALDH1A1BCHECES1 | |
| SCHEMBL25304375 | 0.83 | ALDH1A1 (0.33) | GPR27RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL24670209 | 0.82 | KDM1A (0.43) | GPR27RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL1313097 | 0.81 | BCHE (0.39) | RAB9ASMN1; SMN2HPGDALDH1A1BCHE | |
| SCHEMBL17244914 | 0.80 | RAB9A (0.46) | GPR27RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2796102 | 0.80 | HSD17B10 (0.44) | GPR27HPGDTSHRALDH1A1 | |
| SCHEMBL10630755 | 0.79 | ALDH1A1 (0.33) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL11670395 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDALDH1A1BCHECES1 | |
| Hydrochloric Acid SCHEMBL7670687 | 0.78 | HSD17B10 (0.42) | GPR27HPGDTSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |