Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540113 | 0.77 | — | — | |
| SCHEMBL1702141 | 0.74 | MAPT (0.48) | CA1CA2CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL19104218 | 0.74 | GAA (0.48) | CA1CA2IDO1CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28442749 | 0.74 | APP (0.55) | APPCA1CA2IDO1CA12 | |
| SCHEMBL1758402 | 0.72 | ALDH1A1 (0.46) | CA1CA2IDO1CA12CA9 | |
| SCHEMBL2087066 | 0.72 | CA1 (0.39) | APPCA1CA2IDO1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1408051 | 0.72 | MAPT (0.46) | CA1CA2CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL10495949 | 0.72 | ALDH1A1 (0.50) | APPCA1CA2SIGMAR1CA12 | |
| SCHEMBL31212784 | 0.72 | ALDH1A1 (0.67) | APPCA1CA2IDO1CYP1A2 | |
| SCHEMBL680309 | 0.72 | ACHE (0.41) | IDO1CYP1A2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069884-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |