Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7675349 | 0.99 | TLR8 (0.43) | TLR8KMT2ACASP6 | |
| SCHEMBL7676543 | 0.97 | TLR8 (0.43) | TLR8KMT2ACASP6PIK3CD | |
| SCHEMBL7679455 | 0.94 | TLR8 (0.39) | TLR8KMT2ACASP6PIK3CD | |
| SCHEMBL7675367 | 0.89 | TLR8 (0.42) | TLR8PIK3CD | |
| SCHEMBL7675578 | 0.84 | TLR8 (0.38) | TLR8 | |
| SCHEMBL7889170 | 0.84 | TLR8 (0.38) | TLR8 | |
| SCHEMBL7672108 | 0.83 | DRD3 (0.41) | TLR8 | |
| SCHEMBL7669705 | 0.83 | CYP1A2 (0.36) | TLR8 | |
| Hydrochloric Acid SCHEMBL7672218 | 0.78 | TLR8 (0.44) | TLR8KMT2A | |
| SCHEMBL7670929 | 0.76 | TYMS (0.43) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479514-B1 | FOR THE CONTROL OF HELICOBACTER BACTERIA IN INFECTED PATIENTS | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1086094-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999061438-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |