Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675578 | 0.98 | TLR8 (0.38) | TLR8CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7669705 | 0.95 | CYP1A2 (0.36) | TLR8CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7891586 | 0.86 | TLR8 (0.38) | TLR8CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7676543 | 0.85 | TLR8 (0.43) | TLR8 | |
| SCHEMBL7675367 | 0.84 | TLR8 (0.42) | TLR8 | |
| SCHEMBL7670968 | 0.84 | TLR8 (0.44) | TLR8 | |
| Hydrochloric Acid SCHEMBL7675349 | 0.83 | TLR8 (0.43) | TLR8 | |
| SCHEMBL7679455 | 0.81 | TLR8 (0.39) | TLR8ALDH1A1LMNAHPGD | |
| SCHEMBL7675307 | 0.78 | FLT1 (0.42) | HTTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL7672108 | 0.76 | DRD3 (0.41) | TLR8CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086094-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999061438-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |