Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670968 | 0.83 | TLR8 (0.44) | TLR8 | |
| Hydrochloric Acid SCHEMBL7675349 | 0.82 | TLR8 (0.43) | TLR8 | |
| SCHEMBL7676543 | 0.82 | TLR8 (0.43) | TLR8 | |
| SCHEMBL7679455 | 0.80 | TLR8 (0.39) | TLR8KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7672106 | 0.79 | DRD2 (0.39) | DRD3DRD2CYP1A2CYP2D6ACP1 | |
| SCHEMBL7889170 | 0.76 | TLR8 (0.38) | CYP1A2CYP2D6TLR8ALDH1A1 | |
| SCHEMBL7675578 | 0.76 | TLR8 (0.38) | CYP1A2CYP2D6TLR8ALDH1A1 | |
| SCHEMBL7669705 | 0.75 | CYP1A2 (0.36) | CYP1A2CYP2D6TLR8ALDH1A1 | |
| SCHEMBL7670929 | 0.72 | TYMS (0.43) | ALDH1A1 | |
| SCHEMBL8915135 | 0.70 | RAB9A (0.54) | CYP1A2CYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479514-B1 | FOR THE CONTROL OF HELICOBACTER BACTERIA IN INFECTED PATIENTS | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1086094-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999061438-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |