Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671299 | 1.00 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1ALOX5MEN1 | |
| SCHEMBL7667639 | 0.89 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7667633 | 0.89 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7661071 | 0.89 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7661061 | 0.89 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7672365 | 0.87 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1ALOX5MEN1 | |
| SCHEMBL7672362 | 0.87 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1ALOX5MEN1 | |
| SCHEMBL7669169 | 0.87 | OGA (0.52) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7669163 | 0.87 | OGA (0.52) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL7667849 | 0.87 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355641-B1 | HYPOTENSIVE AGENTS AND WOUND HEALING AGENTS | SYNTEX (U.S.A.) LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2000055143-A1 | OXAZOLONE DERIVATIVES AND THEIR USE AS ALPHA-1 ADRENORECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-09-21 | — | — | WO | disclosed |