Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669163 | 1.00 | OGA (0.52) | OGARAB9AHTTL3MBTL1MEN1 | |
| SCHEMBL7671301 | 0.87 | RAB9A (0.46) | RAB9AL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7671299 | 0.87 | RAB9A (0.46) | RAB9AL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7667633 | 0.85 | RAB9A (0.59) | RAB9AL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7667639 | 0.85 | RAB9A (0.59) | RAB9AL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7672365 | 0.84 | RAB9A (0.49) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7672362 | 0.84 | RAB9A (0.49) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7667849 | 0.83 | RAB9A (0.48) | RAB9AL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7667843 | 0.83 | RAB9A (0.48) | RAB9AL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7663710 | 0.83 | LMNA (0.48) | RAB9AL3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355641-B1 | HYPOTENSIVE AGENTS AND WOUND HEALING AGENTS | SYNTEX (U.S.A.) LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2000055143-A1 | OXAZOLONE DERIVATIVES AND THEIR USE AS ALPHA-1 ADRENORECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-09-21 | — | — | WO | disclosed |