SCHEMBL7671646

SCHEMBL7671646

CCCCCNC(=O)[C@H](Cc1ccc(OCC(=O)OC)c(I)c1)NC(=O)OC(C)(C)C

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 20/20 0.63
PTPRA P18433 1/20 0.49
PTPN22 Q9Y2R2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571372 0.84 PTPN1 (0.88) PTPN1PTPRAPTPN22
SCHEMBL7066343 0.83 PTPN1 (0.57) PTPN1PTPRA
SCHEMBL7680159 0.83 PTPN1 (0.56) PTPN1PTPRAPTPN22
SCHEMBL6574804 0.79 PTPN1 (0.86) PTPN1PTPRAPTPN22
SCHEMBL7674542 0.79 PTPN1 (0.65) PTPN1PTPRAPTPN22
SCHEMBL7569835 0.78 PTPN1 (0.67) PTPN1PTPRA
SCHEMBL7066496 0.78 PTPN1 (0.66) PTPN1PTPRAPTPN22
SCHEMBL12706539 0.78 CTSS (0.51) PTPN1
SCHEMBL6575372 0.77 PTPN1 (1.00) PTPN1PTPRAPTPN22
SCHEMBL7064468 0.77 PTPN1 (0.61) PTPN1PTPRAPTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410585-B1 THERAPY FOR NON-INSULIN DEPEND DIABETES BIOVITRUM AB (SE) 2002-06-25 US disclosed