Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 17/20 | 0.65 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680159 | 0.95 | PTPN1 (0.56) | PTPN1PTPN22PTPRACTSSCTSL | |
| SCHEMBL6571372 | 0.85 | PTPN1 (0.88) | PTPN1PTPN22PTPRA | |
| SCHEMBL6574804 | 0.81 | PTPN1 (0.86) | PTPN1PTPN22PTPRACTSSCTSL | |
| SCHEMBL7671646 | 0.79 | PTPN1 (0.63) | PTPN1PTPN22PTPRA | |
| SCHEMBL6575372 | 0.79 | PTPN1 (1.00) | PTPN1PTPN22PTPRA | |
| SCHEMBL7694481 | 0.77 | PTPN1 (0.87) | PTPN1PTPN22PTPRA | |
| SCHEMBL6574901 | 0.77 | PTPN1 (0.87) | PTPN1PTPN22PTPRA | |
| SCHEMBL6574868 | 0.77 | PTPN1 (0.87) | PTPN1PTPN22PTPRACTSSCTSL | |
| SCHEMBL7064457 | 0.77 | CTSK (0.69) | PTPN1PTPRACTSSCTSLCTSB | |
| SCHEMBL31628751 | 0.76 | PTPN1 (0.68) | PTPN1PTPRACTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |