Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | VDR | P11473 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673162 | 0.88 | MEN1 (0.83) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL23743253 | 0.87 | MAPT (0.72) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7664522 | 0.85 | CYP1A2 (0.78) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL23743154 | 0.84 | MAPT (0.59) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL28147437 | 0.80 | ADORA2A (0.68) | MEN1KMT2AMAPTCYP1A2KDM4E | |
| SCHEMBL13971395 | 0.78 | KDM4E (0.64) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL16404287 | 0.78 | CYP1A2 (0.68) | MEN1KMT2AMAPTCYP1A2KDM4E | |
| SCHEMBL7671927 | 0.78 | TSHR (0.69) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL1083965 | 0.77 | MAPT (0.81) | GAAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL31529342 | 0.77 | MAPT (0.81) | GAAMEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |