SCHEMBL7672003

SCHEMBL7672003

CC(C)OC(=O)C1C(C2CC2)OC(=O)N1C(C)c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.42
METAP2 P50579 1/20 0.37
METAP1 P53582 1/20 0.37
CASR P41180 1/20 0.35
XIAP P98170 2/20 0.35
SSTR4 P31391 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7663425 0.87 METAP2 (0.42) HSD11B1METAP2METAP1CASR
SCHEMBL7668249 0.86 HSD11B1 (0.40) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7667608 0.86 HSD11B1 (0.40) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7667577 0.84 HSD11B1 (0.39) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7670459 0.82 HSD11B1 (0.37) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7670457 0.82 HSD11B1 (0.37) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7687039 0.79 METAP2 (0.39) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7667565 0.79 HSD11B1 (0.36) HSD11B1METAP2METAP1CASRXIAP
SCHEMBL7667659 0.79 KDM4E (0.38)
SCHEMBL7671032 0.76 HSD11B1 (0.41) HSD11B1CASRXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed