Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672505 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7665880 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7668412 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7670466 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7672624 | 0.88 | ALDH1A1 (0.39) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7668397 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7669707 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDCA1CA2NPSR1 | |
| SCHEMBL7667576 | 0.77 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL7667651 | 0.77 | CYP2D6 (0.39) | KMT2AMAPK1MAPTTSHR | |
| SCHEMBL7672014 | 0.77 | CYP2D6 (0.39) | KMT2AMAPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414160-B1 | REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST | UBE INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1000937-A1 | PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS | UBE INDUSTRIES LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |