Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 5/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672014 | 1.00 | CYP2D6 (0.39) | CYP2D6MAPK1MAPTPOLBCYP3A4 | |
| SCHEMBL7663184 | 0.89 | ALDH1A1 (0.36) | MAPK1IDH1KCNA5KMT2A | |
| SCHEMBL4681146 | 0.88 | CYP2D6 (0.40) | CYP2D6MAPK1POLBCYP3A4CYP1A2 | |
| SCHEMBL7663743 | 0.88 | ALDH1A1 (0.38) | IDH1KCNA5KMT2AATM | |
| SCHEMBL7671908 | 0.86 | HIF1A (0.43) | MAPK1MAPTHSD17B10KMT2AATM | |
| SCHEMBL7674321 | 0.86 | CHRM4 (0.44) | KMT2AATM | |
| SCHEMBL7674192 | 0.86 | MAPT (0.39) | CYP2D6MAPK1MAPTCYP3A4CYP1A2 | |
| SCHEMBL7665863 | 0.86 | CYP2D6 (0.40) | CYP2D6MAPK1MAPTPOLBCYP3A4 | |
| SCHEMBL7672498 | 0.86 | MAPT (0.39) | CYP2D6MAPK1MAPTCYP3A4CYP1A2 | |
| SCHEMBL7671107 | 0.84 | EDNRB (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414160-B1 | REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST | UBE INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1000937-A1 | PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS | UBE INDUSTRIES LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |