SCHEMBL7672164

SCHEMBL7672164

COC(=O)C1C(C=Cc2ccccc2)OC(=O)N1C(C)c1cccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASR P41180 3/20 0.37
HSD11B1 P28845 2/20 0.36
GPR139 Q6DWJ6 1/20 0.35
ALDH1A1 P00352 1/20 0.34
NPBWR1 P48145 1/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7672169 1.00 CASR (0.37) CASRHSD11B1GPR139ALDH1A1NPBWR1
SCHEMBL7672160 1.00 CASR (0.37) CASRHSD11B1GPR139ALDH1A1NPBWR1
SCHEMBL7670836 0.82 KDM4E (0.38) CASRHSD11B1GPR139
SCHEMBL7670838 0.82 KDM4E (0.38) CASRHSD11B1GPR139
SCHEMBL7670845 0.82 KDM4E (0.38) CASRHSD11B1GPR139
SCHEMBL7672054 0.82 HSD11B1 (0.39) CASRHSD11B1GPR139
SCHEMBL7667907 0.82 HSD11B1 (0.39) CASRHSD11B1GPR139
SCHEMBL7668338 0.81 HSD11B1 (0.41) CASRHSD11B1GPR139
SCHEMBL7674018 0.81 HSD11B1 (0.41) CASRHSD11B1GPR139ALDH1A1
SCHEMBL7671032 0.81 HSD11B1 (0.41) CASRHSD11B1GPR139ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
EP-1000937-A1 PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS UBE INDUSTRIES LIMITED (JP) 2000-05-17 EP disclosed