Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677849 | 0.81 | BCHE (0.51) | OPRD1OPRK1KDM1AGPR119TSHR | |
| SCHEMBL6155331 | 0.78 | AVPR1A (0.48) | KDM1AGPR119TSHRALOX15ATM | |
| SCHEMBL7675375 | 0.76 | DRD2 (0.55) | — | |
| SCHEMBL6397994 | 0.76 | MAPK1 (0.45) | OPRD1OPRK1KDM1AGPR119TSHR | |
| SCHEMBL1195959 | 0.76 | NR1H2 (0.51) | OPRD1OPRK1KDM1AGPR119PDK2 | |
| SCHEMBL31185482 | 0.76 | MAPK1 (0.45) | OPRD1OPRK1KDM1AGPR119TSHR | |
| SCHEMBL1195957 | 0.76 | NR1H2 (0.51) | OPRD1OPRK1KDM1AGPR119PDK2 | |
| SCHEMBL20511867 | 0.76 | OPRD1 (0.49) | OPRD1OPRK1KDM1AGPR119TSHR | |
| SCHEMBL29993143 | 0.76 | OPRD1 (0.49) | OPRD1OPRK1KDM1AGPR119TSHR | |
| SCHEMBL7675108 | 0.76 | POLB (0.52) | OPRD1OPRK1KDM1AGPR119TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |