Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758331 | 0.98 | CA1 (0.45) | CA1CA2CA9CA7MYC | |
| SCHEMBL7672294 | 0.80 | CA9 (0.43) | CA1CA2CA9CA7MEN1 | |
| SCHEMBL8501585 | 0.76 | SMN1; SMN2 (0.35) | CA1CA2CA9CA7LMNA | |
| SCHEMBL511774 | 0.75 | CA1 (0.50) | CA1CA2TDP1LMNAMYC | |
| SCHEMBL11708793 | 0.73 | CA1 (0.49) | CA1CA2TDP1LMNAMYC | |
| SCHEMBL1487076 | 0.73 | CA1 (0.49) | CA1CA2TDP1LMNAMYC | |
| SCHEMBL13826361 | 0.71 | CA1 (0.46) | CA1CA2TDP1LMNAKDM4E | |
| SCHEMBL7666039 | 0.70 | CA1 (0.43) | CA1CA2MYCKDM4EMEN1 | |
| SCHEMBL7659060 | 0.67 | CA1 (0.40) | CA1CA2MYCKDM4EMEN1 | |
| SCHEMBL8184584 | 0.65 | CA1 (0.42) | CA1CA2MYCKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376540-B1 | PREVENT NEURODEGENERATIVE DISEASE | CENTAUR PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1021430-A1 | FURAN NITRONE COMPOUNDS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| US-6051571-A | NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-6040444-A | Process for preparing furan nitrone compounds | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-03-21 | — | — | US | disclosed |
| WO-1998003496-A1 | FURAN NITRONE COMPOUNDS | CENTAUR PHARMACEUTICALS, INC. (US) | 1998-01-29 | — | — | WO | disclosed |