Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501166 | 0.81 | CA1 (0.31) | CA1CA2CA7CA9 | |
| SCHEMBL7672294 | 0.77 | CA9 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7758331 | 0.77 | CA1 (0.45) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL7673071 | 0.75 | CA12 (0.38) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL7664608 | 0.72 | CA12 (0.35) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL7671014 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL8498723 | 0.71 | LMNA (0.36) | SMN1; SMN2GAALMNAALDH1A1PKM | |
| SCHEMBL8498427 | 0.70 | ATM (0.43) | SMN1; SMN2MEN1POLBKMT2ALMNA | |
| SCHEMBL7669753 | 0.70 | CA12 (0.33) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL7665563 | 0.69 | CA12 (0.33) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942507-A | REAGANTS FOR DETECTION FREE RADICALS | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-08-24 | — | — | US | disclosed |