Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141853 | 0.88 | RAB9A (0.67) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL28849404 | 0.87 | SMN1; SMN2 (0.72) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL19654563 | 0.86 | KMT2A (0.62) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL4124085 | 0.85 | MAPT (0.81) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL584215 | 0.83 | KMT2A (0.65) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL4920497 | 0.82 | MAPT (0.75) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL971445 | 0.81 | KMT2A (0.63) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL3092388 | 0.81 | KMT2A (0.63) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL27334690 | 0.81 | SMN1; SMN2 (0.62) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A | |
| SCHEMBL28142629 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1KMT2ATSHRSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | ALDH1A1 2588/4885KMT2A 3855/4885TSHR 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.