Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923151 | 0.80 | CYP1A2 (0.52) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL7670566 | 0.77 | CYP1A2 (0.49) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL4610282 | 0.77 | CYP1A2 (0.47) | CYP1A2MMP1MMP9MAPT | |
| Hydrochloric Acid SCHEMBL7749595 | 0.76 | CYP1A2 (0.47) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL13548291 | 0.76 | CYP1A2 (0.47) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL5720341 | 0.75 | CYP1A2 (0.48) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL27397452 | 0.74 | MGAM (0.51) | CYP1A2PDGFRBPDGFRAMGAMMAOB | |
| SCHEMBL28287842 | 0.73 | CYP1A2 (0.47) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM | |
| SCHEMBL4371898 | 0.72 | SLC6A2 (0.48) | ALDH1A1CYP1A2HIF1ASMN1; SMN2 | |
| SCHEMBL151560 | 0.71 | CYP1A2 (0.57) | ALDH1A1CYP1A2PDGFRBPDGFRAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052509-A1 | Calcilytic compounds and method of use | SMITHKLINE BEECHAM CORPORATION | 2002-05-02 | — | — | US | disclosed |
| EP-1069901-A4 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORP (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1069901-A1 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051241-A1 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052509-A1 | Calcilytic compounds and method of use | SOST, CALCR, PTH1R | ALDH1A1 3299/4885ATG4B 2101/4885CYP1A2 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.