Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28311359 | 0.91 | FNTA (0.42) | SLC6A2TAAR1LMNACYP2D6FDPS | |
| SCHEMBL3293297 | 0.83 | SLC6A2 (0.48) | SLC6A2TAAR1LMNACYP2D6FDPS | |
| SCHEMBL5527114 | 0.82 | ACHE (0.43) | LMNAALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL99082 | 0.82 | FDPS (0.44) | SLC6A2LMNAFDPSCYP2C9ALDH1A1 | |
| SCHEMBL2838054 | 0.81 | SLC6A2 (0.50) | SLC6A2TAAR1LMNACYP2D6FDPS | |
| SCHEMBL10831201 | 0.80 | SLC6A2 (0.55) | SLC6A2TAAR1LMNACYP2D6FDPS | |
| SCHEMBL5830105 | 0.80 | ESR1 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL97944 | 0.80 | LOXL2 (0.52) | CYP2C19CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL10305277 | 0.80 | MAPT (0.37) | TAAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19610232 | 0.79 | FDPS (0.47) | SLC6A2TAAR1LMNAFDPSCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097384-A1 | INDOZALYL SULPHONAMIDE DERIVATIVES USEFUL AS GLUCOCORTICOID MODULATORS | AstraZeneca AB (SE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008063116-A1 | INDOZALYL SULPHONAMIDE DERIVATIVES USEFUL AS GLUCOCORTICOID MODULATORS | ASTRAZENECA AB (SE) | 2008-05-29 | — | — | WO | disclosed |
| US-4024185-A | REDUCTION OF AROMATIC DINITRO COMPOUNDS | ALLIED CHEMICAL CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |