SCHEMBL7672841

SCHEMBL7672841

C=CCC1(C)C(=C(C#N)C#N)c2ccccc2C1=C(C#N)C#N

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
HTT P42858 1/20 0.38
ALDH1A1 P00352 3/20 0.35
GPR35 Q9HC97 1/20 0.35
MAPT P10636 2/20 0.33
PGR P06401 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7597606 0.71 PGR (0.41) GAAALDH1A1PGR
SCHEMBL8071793 0.68 ALDH1A1 (0.40) GAAHTTALDH1A1MAPTPGR
SCHEMBL15049800 0.65 HTR2A (0.34) ALDH1A1MAPTPGRMAPK1
SCHEMBL19973071 0.64
SCHEMBL3999190 0.62 PGR (0.38) GAAALDH1A1MAPTPGRMEN1
SCHEMBL19973061 0.62
SCHEMBL7260521 0.61 NPC1 (0.37) GAAHTTALDH1A1MAPTMEN1
SCHEMBL28376197 0.60 PGR (0.34) ALDH1A1PGR
SCHEMBL21938552 0.60 PIM1 (0.38) GAAHTTALDH1A1GPR35MAPT
Alcohol SCHEMBL28871387 0.59 PGR (0.43) GAAALDH1A1PGRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230296995-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230056801-A1 Electrophotographic Photoreceptor, Electrophotographic Photoreceptor Cartridge, and Image Forming Device MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-23 US disclosed
US-11073771-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device including the same FUJI ELECTRIC CO., LTD. (JP) 2021-07-27 US disclosed
US-20210124279-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF MANUFACTURING THE PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2021-04-29 US disclosed
US-20210026259-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE INCLUDING THE SAME FUJI ELECTRIC CO., LTD. (JP) 2021-01-28 US disclosed
US-20190025719-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FOR POSITIVE CHARGING, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2019-01-24 US disclosed
US-8846279-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-09-30 US disclosed
US-20130230800-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-09-05 US disclosed
US-6500552-B1 HYDROLYSIS OF MERCAPTOALKYLSILANE COMPOUND; WEAR RESISTANCE, BONDING STRENGTH AEG ELEKTROFOTOGRAFIE GMBH (DE) 2002-12-31 US disclosed