Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.69 |
| ▸ | CA9 | Q16790 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 6/20 | 0.67 |
| ▸ | MAOA | P21397 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595105 | 1.00 | CA12 (0.69) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL7163440 | 0.90 | MIF (0.67) | CA12CA9MAOBMAOAPOLB | |
| Salicyladehyde SCHEMBL29093217 | 0.87 | MAOB (0.55) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL27951961 | 0.86 | CA12 (0.74) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL27951953 | 0.84 | POLB (0.75) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL29592689 | 0.84 | POLB (0.52) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL2249264 | 0.84 | POLB (0.52) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL28340062 | 0.83 | CA12 (0.59) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL9813879 | 0.82 | MAOB (0.67) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL30595106 | 0.82 | MAOB (0.78) | CA12CA9MAOBMAOACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626730-B | A kind of preparation method of Coumarin-3-carboxylic ester derivant | 安徽师范大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-103626730-A | Preparation method for coumarin-3-carboxylic ester derivative | UNIV ANHUI NORMAL | 2014-03-12 | — | — | CN | disclosed |
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |
| US-4201783-A | Antidepressant substituted hexahydro benzopyrano [3,2-c] pyridines | LIPHA LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-05-06 | — | — | US | disclosed |