Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA4 | P22748 | 3/20 | 0.67 |
| ▸ | CA7 | P43166 | 3/20 | 0.67 |
| ▸ | CA3 | P07451 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163440 | 0.89 | MIF (0.67) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL10849691 | 0.87 | MAOB (0.61) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL9813843 | 0.84 | MAOB (0.72) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL7672880 | 0.82 | CA12 (0.69) | MAOBKDM4EGAAALDH1A1CA12 | |
| SCHEMBL30595105 | 0.82 | CA12 (0.69) | MAOBKDM4EGAAALDH1A1CA12 | |
| SCHEMBL10795678 | 0.81 | MIF (0.69) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL24176814 | 0.81 | ALDH1A1 (0.82) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL1406462 | 0.81 | MAOB (1.00) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL2394277 | 0.78 | MAOB (0.77) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL16418952 | 0.78 | KDM4E (0.77) | MAOBKDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110682-B1 | ACTIVATED ARYL CAPPED FLUORESCENT COMPOUNDS, AND ASSAY METHODS AND SYSTEMS USING THEM AS FLUOROGENIC PRECURSORS | SYVA COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4857455-A | WATER SOLUBLE ACTIVATED CAPPED AROMATIC FLUORESCENT COMPOUNDS | SYNTEX (U.S.A) INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0110682-A2 | Activated aryl capped fluorescent compounds, and assay methods and systems using them as fluorogenic precursors | SYVA COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |