Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672982 | 0.81 | MAPT (0.52) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815564 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6814804 | 0.80 | ALDH1A1 (0.74) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6811246 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6816245 | 0.79 | KMT2A (0.76) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7672986 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815021 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815634 | 0.77 | NPC1 (0.68) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815238 | 0.76 | KMT2A (0.77) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815822 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410571-B1 | VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-25 | — | — | US | disclosed |