Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811246 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6814804 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815564 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815021 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6816245 | 0.82 | KMT2A (0.76) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815633 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7672976 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815238 | 0.79 | KMT2A (0.77) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815013 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6815881 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KMT2AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410571-B1 | VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-25 | — | — | US | disclosed |