Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665821 | 0.92 | OPRD1 (0.68) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7673036 | 0.89 | OPRD1 (0.51) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7666959 | 0.84 | OPRD1 (0.59) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7670040 | 0.84 | OPRD1 (0.65) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7673437 | 0.83 | OPRD1 (0.64) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7660627 | 0.82 | OPRD1 (0.65) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6600476 | 0.82 | OPRD1 (0.55) | OPRD1OPRK1OPRM1PDE4B | |
| SCHEMBL7665640 | 0.81 | OPRD1 (0.75) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6598969 | 0.81 | OPRD1 (0.66) | OPRD1OPRK1OPRM1PDE4B | |
| SCHEMBL7671965 | 0.81 | OPRD1 (0.73) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444679-B1 | NEUROLOGICAL AND GASTROINTESTINAL DISORDERS; DELTA OPIOID LIGANDS OR OPIOID RECEPTORS | PFIZER INC | 2002-09-03 | — | — | US | disclosed |
| EP-1038872-A1 | 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands | Pfizer Products Inc. (US) | 2000-09-27 | — | — | EP | disclosed |