Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.56 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.56 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673022 | 1.00 | KDM4E (0.62) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL30634275 | 0.84 | TTR (0.59) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL7674470 | 0.81 | RAB9A (0.58) | KDM4EKMT2ATTRAPPIP6K1 | |
| SCHEMBL7674464 | 0.81 | RAB9A (0.58) | KDM4EKMT2ATTRAPPIP6K1 | |
| SCHEMBL15666341 | 0.80 | MAPT (0.50) | KDM4EKMT2ATTRAPPIP6K1 | |
| SCHEMBL15666344 | 0.80 | MAPT (0.50) | KDM4EKMT2ATTRAPPIP6K1 | |
| SCHEMBL5673590 | 0.80 | KDM4E (0.62) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL5673587 | 0.80 | KDM4E (0.62) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL21620882 | 0.79 | APP (0.69) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL16595912 | 0.78 | KMT2A (0.69) | KDM4EKMT2ASMN1; SMN2TTRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420363-B1 | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2002-07-16 | — | — | US | claimed |