Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.54 |
| ▸ | IP6K3 | Q96PC2 | 4/20 | 0.54 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674470 | 1.00 | RAB9A (0.58) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7673025 | 0.81 | KDM4E (0.62) | RAB9AIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL7673022 | 0.81 | KDM4E (0.62) | RAB9AIP6K1IP6K3IP6K2ALDH1A1 | |
| Phenazine SCHEMBL28375190 | 0.79 | ALDH1A1 (0.56) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26634039 | 0.77 | RAB9A (0.59) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26634059 | 0.77 | RAB9A (0.59) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30634275 | 0.77 | TTR (0.59) | RAB9AKDM4ECYP3A4CA12AKR1B10 | |
| SCHEMBL78426 | 0.77 | RELA (0.62) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL78427 | 0.77 | RELA (0.62) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29462468 | 0.77 | RELA (0.62) | RAB9AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420363-B1 | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| WO-2023212565-A2 | MOLECULAR EDITING OF MULTIPLE C-H BONDS BY LEVERAGING RECOGNITION OF DISTANCE, GEOMETRY AND CHIRALITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | WO | disclosed |