Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585551 | 0.85 | CNR1 (0.46) | ALDH1A1TAAR1CNR1LMNATP53 | |
| SCHEMBL7872178 | 0.85 | CNR1 (0.46) | TAAR1CNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL7589548 | 0.85 | HDAC3 (0.36) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL6816639 | 0.83 | KMT2A (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL7588694 | 0.82 | RAB9A (0.51) | ALDH1A1SMN1; SMN2CNR1RAB9AHTT | |
| SCHEMBL7865609 | 0.81 | TRPV1 (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL3305183 | 0.80 | CNR1 (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL7868217 | 0.78 | HIF1A (0.47) | TAAR1CNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL7594776 | 0.77 | HPGD (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL7599731 | 0.77 | CNR1 (0.42) | ALDH1A1SMN1; SMN2KMT2AHPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407123-B1 | VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |