SCHEMBL7673265

SCHEMBL7673265

CC1C([Zr+2]C2=Cc3ccccc3C2C)=Cc2ccccc21.[NH-]c1c(F)cccc1F.[NH-]c1c(F)cccc1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31666284 0.83 DRD2 (0.39) BRD4CCL2DRD2DRD4
Fluoride Ion SCHEMBL1130750 0.82 DRD2 (0.38) BRD4CCL2DRD2DRD4
Hydrochloric Acid SCHEMBL1685526 0.82 DRD2 (0.38) BRD4CCL2DRD2DRD4
SCHEMBL30186426 0.67 DRD2 (0.40) BRD4CCL2DRD2DRD4MEN1
Fluoride Ion SCHEMBL1130604 0.66 DRD2 (0.33) DRD2DRD4
Hydrochloric Acid SCHEMBL3670080 0.66 DRD2 (0.33) DRD2DRD4
Hydrochloric Acid SCHEMBL18259385 0.64
SCHEMBL29358733 0.62 DRD2 (0.33) BRD4CCL2DRD2DRD4
Hydrochloric Acid SCHEMBL30209235 0.62 DRD2 (0.33) BRD4CCL2DRD2DRD4
Bromide SCHEMBL27933024 0.62 DRD2 (0.39) BRD4CCL2DRD2DRD4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6339035-B1 CATALYST SYSTEM FORMED BY COMBINING A MONOORGANOAMIDE METALLOCENE SUCH AS BOS(CYCLOPENTADIENYL) ZIRCONIUM BIS(2,6-DIISOPROPYLPHENYLAMIDE) AND A COCATALYST HAVING AN ALKYL ALUMINUM FUNCTIONALITY; OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY 2002-01-15 US disclosed