Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1130604 | 0.97 | DRD2 (0.33) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7540778 | 0.82 | CYP19A1 (0.32) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7546508 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1685526 | 0.81 | DRD2 (0.38) | DRD2DRD4CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL5601013 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5600559 | 0.80 | — | — | |
| SCHEMBL31666284 | 0.79 | DRD2 (0.39) | DRD2DRD4CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8770753 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28732822 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6294317 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294565-B1 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1373404-B1 | POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1299470-B1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1810992-A1 | Polyethylene blends | Univation Technologies, LLC (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7220801-B2 | Metallocene-produced very low density polyethylenes or linear low density polyethylenes as impact modifiers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-22 | — | — | US | disclosed |
| EP-1325073-B1 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | EXXONMOBIL CHEM PATENTS INC (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20060276594-A1 | Very low density polyethylene blends | UNIVATION TECHNOLOGIES, LLC (US) | 2006-12-07 | — | — | US | disclosed |
| US-7135526-B2 | Very low density polyethylene and high density polyethylene blends | UNIVATION TECHNOLOGIES, LLC (US) | 2006-11-14 | — | — | US | disclosed |
| US-7125933-B2 | Very low density polyethylene blends | UNIVATION TECHNOLOGIES, LLC (US) | 2006-10-24 | — | — | US | disclosed |
| US-6953828-B2 | Polymeric membrane compositions | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2005-10-11 | — | — | US | disclosed |
| US-20040072005-A1 | Suitable in blown and cast film applications | UNIVATION TECHNOLOGIES, LLC | 2004-04-15 | — | — | US | disclosed |
| US-20040014895-A1 | Very low density polyethylene and high density polyethylene blends | UNIVATION TECHNOLOGIES, LLC | 2004-01-22 | — | — | US | disclosed |
| US-20030215659-A1 | Metallocene-produced very low density polyethylenes | UNIVATION TECHNOLOGIES, LLC | 2003-11-20 | — | — | US | disclosed |
| US-20030213938-A1 | Metallocene-produced very low density polyethylenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-11-20 | — | — | US | disclosed |
| EP-1325073-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | ExxonMobil Chemical Patents Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1299470-A1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1294565-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000436-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2001098409-A1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001098372-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |