⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049676 | 0.88 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL28706950 | 0.84 | CA12 (0.31) | — | |
| SCHEMBL4280278 | 0.84 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL4338021 | 0.84 | — | — | |
| SCHEMBL9645849 | 0.83 | FLT3 (0.35) | — | |
| SCHEMBL9373101 | 0.82 | FLT3 (0.37) | — | |
| SCHEMBL9368674 | 0.81 | ESR1 (0.35) | — | |
| SCHEMBL714018 | 0.78 | KMT2A (0.43) | — | |
| SCHEMBL9402860 | 0.77 | — | — | |
| SCHEMBL3141095 | 0.77 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388072-B2 | TETRAALKYL SUBSTITUTED PIPERIDINE SUBSTITUTED ON THE N-ATOM WITH O-E-OH GROUP (E= ALKYLENE OR PHENYLENE OR CYCLOALIPHATIC DERIVATIVES) ARE USED FOR STABILIZING POLYOLEFINS AND AUTOMOTIVE COATING AGAINST HEAT, OXIDATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-14 | — | — | US | disclosed |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-23 | — | — | US | disclosed |